"Rumination Brain" Rumination can be a headache! You go over and over and over something in your mind. Often what you go over is a problem that doesn't need solving. It's tough to get over, but there are ways to overcome it. If you do ruminate, you need to take action to get over it because it can lead to serious conditions, like depression. Find out what you can do to overcome it. Talk to your doctor if you need to.